Loading with a 1 Kg weight should result in a 1 Hz decrease in frequency in normal subjects and those with enhanced physiological tremor (EPT), whereas change in frequency in ET and PD is usually < 1 Hz1. An effect may also be seen in functional tremor.

The frequency shift is thought to appear because EPT is caused partly by mechanical reflex oscillation, which is dependent on the hand’s resonant frequency and therefore changes with increased inertial loading.



1. Gironell A, Kulisevsky J, Pascual-Sedano B, Barbanoj M. Routine Neurophysiologic Tremor Analysis as a Diagnostic Tool for Essential Tremor: A Prospective Study. J Clin Neurophysiol. 2004;21(6):446-450.